Kejadian Atopi pada Bayi Usia 6 Bulan yang Mendapat Kombinasi ASI dan Susu Formula Mengandung Probiotik dan Nonprobiotik

• Main Authors: Tetty Yuniati, Abdurachman Sukadi
• Format: Article
• Language: English
• Published: Universitas Padjajaran 2011-06-01
• Series: Majalah Kedokteran Bandung
• Subjects: Atopy; caesarean delivery; probiotic
• Online Access: http://journal.fk.unpad.ac.id/index.php/mkb/article/view/45
• ISSN: 0126-074X; 2338-6223

Cesarean delivery might delayed the colonization of newborn intestine and increase atopic disorders. Probiotic shown to stimulate immune responses, which has implied in the development of atopic disorders. The aim of the study was to find out the difference of atopic occurence in breastfed infants born by cesarean delivery given probiotic formula and non probiotic formula. Randomized open label clinical trial was performed on 96 healthy infants, birth weight ≥2,500 g, born by cesarean delivery in Dr. Hasan Sadikin Hospital Bandung during November 2009 to October 2010. Since birth, 48 infants were breastfed combined with probiotic formula and 48 infants as control group for 4 weeks and afterwards the feeding pattern depend on the parents. Skin prick test reaction was performed at 6 months old and atopy was diagnosed if the wheal ≥4 mm. Statistical analysis using chi-square and t-test. The duration of daily breastfeeding, amount of formula and risk factor for atopic disorders were not significantly different in both groups (p>0.05). Atopy were positive in 4/23 infants with probiotic and 10/28 infants positive without probiotic. It was not significantly different (p>0.05). Conclusion, the atopic occurence is not different at 6 months-old receiving breastmilk with probiotic and non probiotic formula.