Deficient sensorimotor gating induced by selective breeding in rats is improved by entopeduncular nucleus lesions

Deficient sensorimotor gating induced by selective breeding in rats is improved by entopeduncular nucleus lesions

Deficient prepulse inhibition (PPI) of startle reflects disturbed sensorimotor gating found in certain neuropsychiatric disorders, such as Tourette's syndrome, ADHD, Huntington's and schizophrenia. We here tested, whether lesions of the entopeduncular nucleus (EPN) would improve a PPI-defi...

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Bibliographic Details
Main Authors: Kerstin Schwabe, Nino Polikashvili, Joachim K. Krauss
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Neurobiology of Disease
Subjects:
Prepulse inhibition
Startle
Locomotor activity
Globus pallidus internus
Basal ganglia
Neuropsychiatric disorders
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000321

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