The Therapeutic Implications of Tea Polyphenols against Dopamine (DA) Neuron Degeneration in Parkinson’s Disease (PD)

The Therapeutic Implications of Tea Polyphenols against Dopamine (DA) Neuron Degeneration in Parkinson’s Disease (PD)

Accumulative evidence indicated that the pathologically accumulated metal ions (iron species and Mn<sup>3+</sup>) and abnormally up-regulated monoamine oxidase B (MAOB) activity induced oxidation of endogenous dopamine (DA) can lead to mitochondria impairment, lysosome dysfunction, prote...

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Bibliographic Details
Main Authors: Zhi Dong Zhou, Shao Ping Xie, Wuan Ting Saw, Patrick Ghim Hoe Ho, Hong Yan Wang, Lei Zhou, Yi Zhao, Eng King Tan
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
dopamine
neurodegeneration
polyphenols
Parkinson’s disease
anti-PD therapy
Online Access:https://www.mdpi.com/2073-4409/8/8/911

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