Structural Dissection of Viral Spike-Protein Binding of SARS-CoV-2 and SARS-CoV-1 to the Human Angiotensin-Converting Enzyme 2 (ACE2) as Cellular Receptor

Structural Dissection of Viral Spike-Protein Binding of SARS-CoV-2 and SARS-CoV-1 to the Human Angiotensin-Converting Enzyme 2 (ACE2) as Cellular Receptor

An outbreak by a new severe acute respiratory syndrome betacoronavirus (SARS-CoV-2) has spread CoronaVirus Disease 2019 (COVID-19) all over the world. Immediately, following studies have confirmed the human Angiotensin-Converting Enzyme 2 (ACE2) as a cellular receptor of viral Spike-Protein (Sp) tha...

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Bibliographic Details
Main Authors: Deborah Giordano, Luigi De Masi, Maria Antonia Argenio, Angelo Facchiano
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
SARS-CoV-1
SARS-CoV-2
COVID-19
human ACE2
viral spike-protein
Receptor-Binding Domain (RBD)
Online Access:https://www.mdpi.com/2227-9059/9/8/1038

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