A novel naturally occurring tandem promoter in modified vaccinia virus ankara drives very early gene expression and potent immune responses.
Modified vaccinia virus Ankara (MVA) has been shown to be suitable for the generation of experimental vaccines against cancer and infectious diseases, eliciting strong humoral and cellular immune responses. In viral vectored vaccines, strong recombinant antigen expression and timing of expression in...
Main Authors: | Sonia T Wennier, Kay Brinkmann, Charlotte Steinhäußer, Nicole Mayländer, Claudia Mnich, Ursula Wielert, Ulrike Dirmeier, Jürgen Hausmann, Paul Chaplin, Robin Steigerwald |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3741161?pdf=render |
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