Celastrol prevents atherosclerosis via inhibiting LOX-1 and oxidative stress.

Celastrol prevents atherosclerosis via inhibiting LOX-1 and oxidative stress.

Celastrol is a triterpenoid compound extracted from the Chinese herb Tripterygium wilfordii Hook F. Previous research has revealed its anti-oxidant, anti-inflammatory, anti-cancer and immunosuppressive properties. Here, we investigated whether celastrol inhibits oxidized low-density lipoprotein (oxL...

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Main Authors: Lei Gu, Wenli Bai, Sha Li, Yuqing Zhang, Yi Han, Yue Gu, Guoliang Meng, Liping Xie, Jing Wang, Yujiao Xiao, Liyang Shan, Suming Zhou, Lei Wei, Albert Ferro, Yong Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3684610?pdf=render

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