A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports
Osteopetrosis is a rare genetic bone disorder arising due to a defect in the differentiation or function of osteoclast which results in a generalized increase in bone mass. Osteomyelitis is one of the most common complications because of decreased bone marrow function and compromised blood supply. R...
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doaj-cfe29794e9e545aeb69e2ea158f686432020-11-24T23:12:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032016-01-0127666767110.4103/0970-9290.199603A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reportsS JayachandranM Suresh KumarOsteopetrosis is a rare genetic bone disorder arising due to a defect in the differentiation or function of osteoclast which results in a generalized increase in bone mass. Osteomyelitis is one of the most common complications because of decreased bone marrow function and compromised blood supply. Radiologist plays a vital role in diagnosing osteopetrosis. Here, we present two cases of autosomal dominant osteopetrosis Type II (ADO II) with secondary osteomyelitis changes which were reported to our department. One of these two cases presented with secondary osteomyelitis in both maxilla and mandible and features of rickets, which is very rarely seen in ADO II. To the best of our knowledge, the presentation of rickets with ADO is the first of its kind to be reported. In this paper, we describe the clinical and radiological features leading to the diagnosis of ADO in these two patients. Further, a review of the literature regarding ADO is discussed.http://www.ijdr.in/article.asp?issn=0970-9290;year=2016;volume=27;issue=6;spage=667;epage=671;aulast=JayachandranAutosomal dominant osteopetrosisbone within boneosteomyelitisrickets |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
S Jayachandran M Suresh Kumar |
spellingShingle |
S Jayachandran M Suresh Kumar A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports Indian Journal of Dental Research Autosomal dominant osteopetrosis bone within bone osteomyelitis rickets |
author_facet |
S Jayachandran M Suresh Kumar |
author_sort |
S Jayachandran |
title |
A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports |
title_short |
A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports |
title_full |
A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports |
title_fullStr |
A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports |
title_full_unstemmed |
A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports |
title_sort |
paradoxical presentation of rickets and secondary osteomyelitis of the jaw in type ii autosomal dominant osteopetrosis: rare case reports |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Dental Research |
issn |
0970-9290 1998-3603 |
publishDate |
2016-01-01 |
description |
Osteopetrosis is a rare genetic bone disorder arising due to a defect in the differentiation or function of osteoclast which results in a generalized increase in bone mass. Osteomyelitis is one of the most common complications because of decreased bone marrow function and compromised blood supply. Radiologist plays a vital role in diagnosing osteopetrosis. Here, we present two cases of autosomal dominant osteopetrosis Type II (ADO II) with secondary osteomyelitis changes which were reported to our department. One of these two cases presented with secondary osteomyelitis in both maxilla and mandible and features of rickets, which is very rarely seen in ADO II. To the best of our knowledge, the presentation of rickets with ADO is the first of its kind to be reported. In this paper, we describe the clinical and radiological features leading to the diagnosis of ADO in these two patients. Further, a review of the literature regarding ADO is discussed. |
topic |
Autosomal dominant osteopetrosis bone within bone osteomyelitis rickets |
url |
http://www.ijdr.in/article.asp?issn=0970-9290;year=2016;volume=27;issue=6;spage=667;epage=671;aulast=Jayachandran |
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