Oleylphosphocholine (OlPC) arrests Cryptosporidium parvum growth in vitro and prevents lethal infection in interferon gamma receptor knock-out mice

Oleylphosphocholine (OlPC) arrests Cryptosporidium parvum growth in vitro and prevents lethal infection in interferon gamma receptor knock-out mice

Cryptosporidium parvum is a species of protozoa that causes cryptosporidiosis, an intestinal disease affecting many mammals including humans. Typically, in healthy individuals, cryptosporidiosis is a self-limiting disease. However, C. parvum can cause a severe and persistent infection that can be l...

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Bibliographic Details
Main Authors: Karine eSonzogni-Desautels, Axel eRenteria Flores, Fabio eVasquez Camargo, Thomas Z Di Lenardo, Alexandre eMikhail, Michael J Arrowood, Anny eFortin, Momar eNdao
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Microbiology
Subjects:
Cryptosporidiosis
Cryptosporidium parvum
Oocysts
miltefosine
parasite burden
Oleylphosphocholine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00973/full

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