Concomitant granular cell tumor and balanitis xerotica obliterans of the foreskin: A case report and literature review

Balanitis xerotica obliterans is a chronic dermatosis that frequently involves the glans penis and the foreskin. Granular cell tumor is a benign tumor that may rarely involve the penis, but involvement of the foreskin is exceedingly rare. It may result in thickening and ulceration of the overlying e...

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Bibliographic Details
Main Authors: Shaun AC Medlicott, MD, FRCPC, Kiril Trpkov, MD, FRCPC
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Human Pathology: Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214330016300712
Description
Summary:Balanitis xerotica obliterans is a chronic dermatosis that frequently involves the glans penis and the foreskin. Granular cell tumor is a benign tumor that may rarely involve the penis, but involvement of the foreskin is exceedingly rare. It may result in thickening and ulceration of the overlying epidermis, which can mimic squamous cell carcinoma. An association of these two lesions, one very common and one extremely uncommon, arising concomitantly in the penile foreskin has not been previously documented. A 23-year-old patient with phimosis and a subcutaneous foreskin nodule presented for a medical circumcision. The microscopic examination demonstrated balanitis xerotica obliterans and granular cell tumor, occurring in continuity in the foreskin. To our knowledge, this is the first reported example of these two lesions arising simultaneously in the male genitalia. Keywords: Granular cell tumor, Balanitis xerotica obliterans, Foreskin, Penis, Glans
ISSN:2214-3300