THE INFLUENCE OF PATHOLOGICAL CARDIO-ANKLE VESSEL INDEX ON ANNUAL RESULTS OF CORONARY BYPASS IN PATIENTS WITH ISCHEMIC HEART DISEASE

• Main Authors: A. N. Sumin, A. V. Shcheglova, T. B. Bashtanova, O. L. Barbarash
• Format: Article
• Language: Russian
• Published: «SILICEA-POLIGRAF» LLC 2015-06-01
• Series: Кардиоваскулярная терапия и профилактика
• Subjects: coronary bypass grafting; cardio-ankle vessel index
• Online Access: https://cardiovascular.elpub.ru/jour/article/view/134
• ISSN: 1728-8800; 2619-0125

Aim. To study interrelations of cardio-ankle vessel index (CAVI) with annual results of coronary bypass grafting (CBG) in patients with ischemic heart disease (CHD).Material and methods. On the first stage, we included 356 patients after CBG. All patients underwent CAVI assessment. In a year we analyzed the condition of 341 patient, and selected patients into groups: I (n=221) — CAVI >9,0 and II (n=120) group — CAVI <9,0. Groups were comparable by the prevalence of cardiovascular events: death, myocardial infarction, stroke, hospitalization, angina onset.Results. In evaluation of the results in long-term period after operation, the mortality was higher in the II group and reached 3,3% relative to I group — 2,3% cases, resp. (p=0,55). In general patients with pathologic CAVI had more common negative prognosis during one year in 34 (28,3%) cases, comparing to patients with normal CAVI — 42 (19,0%) of patients (p=0,048). Probability of combined endpoint occurrence (CEP) increased with the increase of CAVI (p=0,04), with the existence of bilateral carotid stenosis (p=0,01), and in the relation of CBG with therombectomy (p=0,04). In multifactor analysis an independent relation with the risk of CEP was found for bilateral carotid arteries stenosis and increase of CAVI (OR 2,5; 95% CI 1,26-5,08; p-0,008 and OR 1,7; 95% CI 1,0-2,9; p=0,02, resp.).Conclusion. The pathological CAVI was associated with higher prevalence of CEP during one year. In multifactorial analysis an independent influence on prognosis in this kind of patients had CAVI and presence of bilateral carotid stenosis. The assessment of CAVI is aimfull to perform before CBG to find out the patients with increased risk of cardiovascular events.