Association of Static Posturography With Severity of White Matter Hyperintensities
Background: Impaired gait and balance are associated with severity of leukoaraiosis. Evaluation of balance is based on neurological examination using Romberg's test with bipedal standing, assessment scale, and posturographic parameters. The goal of this study was to determine the relationship b...
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doaj-d02ea4f74b2140aca277da8c2405b1322021-02-11T06:25:47ZengFrontiers Media S.A.Frontiers in Neurology1664-22952021-02-011210.3389/fneur.2021.579281579281Association of Static Posturography With Severity of White Matter HyperintensitiesBin Liu0Guifeng Zhao1Ling Jin2Jingping Shi3Department of Geriatrics, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing Brain Hospital, Nanjing, ChinaDepartment Key Laboratory of Research and Application of Animal Models for Environmental and Metabolic Diseases, Sheng Jing Hospital of China Medical University, Shenyang, ChinaDepartment of Geriatrics, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing Brain Hospital, Nanjing, ChinaDepartment of Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing Brain Hospital, Nanjing, ChinaBackground: Impaired gait and balance are associated with severity of leukoaraiosis. Evaluation of balance is based on neurological examination using Romberg's test with bipedal standing, assessment scale, and posturographic parameters. The goal of this study was to determine the relationship between static equilibrium and grades of white matter hyperintensities (WMHs) using static posturography as a quantitative technical method.Method: One hundred and eighteen (118) patients with lacunar infarct were recruited and assessed on MRI with Fazekas's grading scale into four groups. On admission, age, gender, height, weight, Berg Balance Scale (BBS), mini-mental state examination (MMSE), and static posturography parameters were recorded, and their correlations with WMHs were determined.Results: Age was significantly and positively correlated with severity of WMHs (r = 0.39, p < 0.05). WMH score was negatively correlated with BBS score (r = −0.65, p < 0.05) and MMSE score (r = −0.79, p < 0.05). There was a significant positive correlation between track length anteroposterior (AP, with eyes closed) and severity of WMHs (r = 0.70, p < 0.05). Partial correlation analysis and multiple logistic regression analysis indicated that track length AP with eyes closed, was a predictor for the severity of WMHs (p< 0.05).Conclusion: The severity of WHMs is associated with age, cognitive decline, and impairment in balance. Posturography parameter in track length in AP direction with eyes closed in relation to cognition and balance, may be a potential marker for disease progression in WMHs.https://www.frontiersin.org/articles/10.3389/fneur.2021.579281/fullposturographybalancewhite matter hyperintensitiescognitionstroke |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bin Liu Guifeng Zhao Ling Jin Jingping Shi |
spellingShingle |
Bin Liu Guifeng Zhao Ling Jin Jingping Shi Association of Static Posturography With Severity of White Matter Hyperintensities Frontiers in Neurology posturography balance white matter hyperintensities cognition stroke |
author_facet |
Bin Liu Guifeng Zhao Ling Jin Jingping Shi |
author_sort |
Bin Liu |
title |
Association of Static Posturography With Severity of White Matter Hyperintensities |
title_short |
Association of Static Posturography With Severity of White Matter Hyperintensities |
title_full |
Association of Static Posturography With Severity of White Matter Hyperintensities |
title_fullStr |
Association of Static Posturography With Severity of White Matter Hyperintensities |
title_full_unstemmed |
Association of Static Posturography With Severity of White Matter Hyperintensities |
title_sort |
association of static posturography with severity of white matter hyperintensities |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neurology |
issn |
1664-2295 |
publishDate |
2021-02-01 |
description |
Background: Impaired gait and balance are associated with severity of leukoaraiosis. Evaluation of balance is based on neurological examination using Romberg's test with bipedal standing, assessment scale, and posturographic parameters. The goal of this study was to determine the relationship between static equilibrium and grades of white matter hyperintensities (WMHs) using static posturography as a quantitative technical method.Method: One hundred and eighteen (118) patients with lacunar infarct were recruited and assessed on MRI with Fazekas's grading scale into four groups. On admission, age, gender, height, weight, Berg Balance Scale (BBS), mini-mental state examination (MMSE), and static posturography parameters were recorded, and their correlations with WMHs were determined.Results: Age was significantly and positively correlated with severity of WMHs (r = 0.39, p < 0.05). WMH score was negatively correlated with BBS score (r = −0.65, p < 0.05) and MMSE score (r = −0.79, p < 0.05). There was a significant positive correlation between track length anteroposterior (AP, with eyes closed) and severity of WMHs (r = 0.70, p < 0.05). Partial correlation analysis and multiple logistic regression analysis indicated that track length AP with eyes closed, was a predictor for the severity of WMHs (p< 0.05).Conclusion: The severity of WHMs is associated with age, cognitive decline, and impairment in balance. Posturography parameter in track length in AP direction with eyes closed in relation to cognition and balance, may be a potential marker for disease progression in WMHs. |
topic |
posturography balance white matter hyperintensities cognition stroke |
url |
https://www.frontiersin.org/articles/10.3389/fneur.2021.579281/full |
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