Unilateral Dyshidrosiform Pemphigus Vulgaris

• Main Authors: Manju Daroach, Dipankar De, Sanjeev Handa, Rahul Mahajan, Vikarn Vishwajeet, Uma N. Saikia
• Format: Article
• Language: English
• Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-06-01
• Series: Annals of the National Academy of Medical Sciences (India)
• Subjects: pemphigus vulgaris; dyshidrosiform; unilateral
• Online Access: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713184

Pemphigus vulgaris is an autoimmune disease characterized by fluid-filled blisters over body and mucosal surfaces. Localized pemphigus is a rare presentation of the disease. There are few reports of localized pemphigus in literature presenting as esophageal involvement, recurrent paronychia, conjunctival mass, foot ulcers, discoloration of toes with hyperkeratotic skin lesions, verrucous lesions, and dyshidrosiform pemphigus vulgaris. We present a case of dyshidrosiform pemphigus involving a foot following trauma. Histopathology and direct immunofluorescence confirmed our diagnosis. In our patient, the disease started as localized dyshidrosiform pemphigus and later became generalized. This unusual presentation led to a delay in diagnosis and proper treatment in this patient. Physicians should be aware of such rare presentations to aid in the timely diagnosis and management of such patients.