Glutamine treatment attenuates hyperglycemia-induced mitochondrial stress and apoptosis in umbilical vein endothelial cells

Glutamine treatment attenuates hyperglycemia-induced mitochondrial stress and apoptosis in umbilical vein endothelial cells

OBJECTIVE:The aim of this study was to determine the in vitro effect of glutamine and insulin on apoptosis, mitochondrial membrane potential, cell permeability, and inflammatory cytokines in hyperglycemic umbilical vein endothelial cells.MATERIALS AND METHODS:Human umbilical vein endothelial cells w...

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Bibliographic Details
Main Authors: Sher Zaman Safi, Kalaivani Batumalaie, Marzida Mansor, Karuthan Chinna, Syam Mohan, Hamed Karimian, Rajes Qvist, Muhammad Aqeel Ashraf, Garcie Ong Siok Yan
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2015-08-01
Series:Clinics
Subjects:
Hyperglycemia
Sepsis
Apoptosis
Cytokine
Glutamine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322015000800569&lng=en&tlng=en

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