The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis
Abstract Background Reactive oxygen species (ROS) regulate the migration and invasion of fibroblast-like synoviocytes (FLS), which are key effector cells in rheumatoid arthritis (RA) pathogenesis. Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) induces ROS generation and, consequently,...
Main Authors: | Ha-Reum Lee, Su-Jin Yoo, Jinhyun Kim, In Seol Yoo, Chan Keol Park, Seong Wook Kang |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13075-020-02204-0 |
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