Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

Bone marrow niches support multiple myeloma, providing signals and cell-cell interactions essential for disease progression. A 3D bone marrow niche model was developed, in which supportive multipotent mesenchymal stromal cells and their osteogenic derivatives were co-cultured with endothelial progen...

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Bibliographic Details
Main Authors: Maaike V. J. Braham, Monique C. Minnema, Tineke Aarts, Zsolt Sebestyen, Trudy Straetemans, Anna Vyborova, Jurgen Kuball, F. Cumhur Öner, Catherine Robin, Jacqueline Alblas
Format: Article
Language:English
Published: Taylor & Francis Group 2018-06-01
Series:OncoImmunology
Subjects:
bone marrow niche
immunotherapy
multiple myeloma
tumor microenvironment
3d model
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1434465

Internet

http://dx.doi.org/10.1080/2162402X.2018.1434465

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