Coronavirus disease 2019 vaccines: landscape of global studies and potential risks
Abstract. With the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, the importance of vaccines in epidemic prevention and public health has become even more obvious than ever. However, the emergence of multiple severe acute respiratory syndrome coronavirus 2 variants worldwide has raise...
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Wolters Kluwer
2021-09-01
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Series: | Chinese Medical Journal |
Online Access: | http://journals.lww.com/10.1097/CM9.0000000000001688 |
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doaj-d088158a5a3f4b3d82fede271386370e2021-09-28T10:18:16ZengWolters KluwerChinese Medical Journal0366-69992542-56412021-09-01134172037204410.1097/CM9.0000000000001688202109050-00003Coronavirus disease 2019 vaccines: landscape of global studies and potential risksHu-Da-Chuan JiangYan-Yang TaoSi-Yue JiaJing-Xin LiFeng-Cai ZhuJing NiAbstract. With the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, the importance of vaccines in epidemic prevention and public health has become even more obvious than ever. However, the emergence of multiple severe acute respiratory syndrome coronavirus 2 variants worldwide has raised concerns about the effectiveness of current COVID-19 vaccines. Here, we review the characteristics of COVID-19 vaccine candidates in five platforms and the latest clinical trial results of them. In addition, we further discuss future directions for the research and development of the next generation of COVID-19 vaccines. We also summarize the serious adverse events reported recently after the large-scale vaccination with the current COVID-19 vaccines, including the thromboembolism caused by the AstraZeneca and Johnson & Johnson vaccines.http://journals.lww.com/10.1097/CM9.0000000000001688 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hu-Da-Chuan Jiang Yan-Yang Tao Si-Yue Jia Jing-Xin Li Feng-Cai Zhu Jing Ni |
spellingShingle |
Hu-Da-Chuan Jiang Yan-Yang Tao Si-Yue Jia Jing-Xin Li Feng-Cai Zhu Jing Ni Coronavirus disease 2019 vaccines: landscape of global studies and potential risks Chinese Medical Journal |
author_facet |
Hu-Da-Chuan Jiang Yan-Yang Tao Si-Yue Jia Jing-Xin Li Feng-Cai Zhu Jing Ni |
author_sort |
Hu-Da-Chuan Jiang |
title |
Coronavirus disease 2019 vaccines: landscape of global studies and potential risks |
title_short |
Coronavirus disease 2019 vaccines: landscape of global studies and potential risks |
title_full |
Coronavirus disease 2019 vaccines: landscape of global studies and potential risks |
title_fullStr |
Coronavirus disease 2019 vaccines: landscape of global studies and potential risks |
title_full_unstemmed |
Coronavirus disease 2019 vaccines: landscape of global studies and potential risks |
title_sort |
coronavirus disease 2019 vaccines: landscape of global studies and potential risks |
publisher |
Wolters Kluwer |
series |
Chinese Medical Journal |
issn |
0366-6999 2542-5641 |
publishDate |
2021-09-01 |
description |
Abstract. With the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, the importance of vaccines in epidemic prevention and public health has become even more obvious than ever. However, the emergence of multiple severe acute respiratory syndrome coronavirus 2 variants worldwide has raised concerns about the effectiveness of current COVID-19 vaccines. Here, we review the characteristics of COVID-19 vaccine candidates in five platforms and the latest clinical trial results of them. In addition, we further discuss future directions for the research and development of the next generation of COVID-19 vaccines. We also summarize the serious adverse events reported recently after the large-scale vaccination with the current COVID-19 vaccines, including the thromboembolism caused by the AstraZeneca and Johnson & Johnson vaccines. |
url |
http://journals.lww.com/10.1097/CM9.0000000000001688 |
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