Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report
Abstract Background Laterality disorders of the abdominal organs include situs inversus totalis that mirrors the arrangements of all internal organs and heterotaxy syndrome (situs ambiguus) in which the thoracic or abdominal organs are abnormally arranged. Heterotaxy is often accompanied by multiple...
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doaj-d093874bb2df4cb4b8401ebc58bd37f42020-11-25T00:29:49ZengBMCBMC Veterinary Research1746-61482017-09-0113111010.1186/s12917-017-1213-2Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case reportDaisuke Kondoh0Tomomi Kawano1Tomoaki Kikuchi2Kaoru Hatate3Kenichi Watanabe4Motoki Sasaki5Norio Yamagishi6Hisashi Inokuma7Nobuo Kitamura8Division of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineDivision of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary MedicineAbstract Background Laterality disorders of the abdominal organs include situs inversus totalis that mirrors the arrangements of all internal organs and heterotaxy syndrome (situs ambiguus) in which the thoracic or abdominal organs are abnormally arranged. Heterotaxy is often accompanied by multiple congenital malformations, and it generally comprises asplenia and polysplenia syndromes. To our knowledge, polysplenia syndrome has been reported in only three cattle, and computerized tomographic (CT) images of these animals were not obtained. Case presentation A six-month-old Holstein heifer had ruminal tympani and right abdominal distension. CT imaging showed that the rumen occupied the right side of the abdominal cavity, the omasum and abomasum occupied the left ventral side and the liver was positioned on the left. The colon and cecum were located at the left dorsum of the cavity, and the left kidney was located more cranially than the right. Postmortem findings revealed two spleens attached to the rumen. Significantly, the duodenum was too short to be divided into segments, except the cranial and descending parts, or flexures, except the cranial flexure, and the pancreas, which lacked a left lobe, was covered with mesojejunum. The liver comprised a relatively large right lobe and a small left lobe without quadrate and caudate lobes. The caudal vena cava that connected to the left azygous vein passed irregularly through the aortic hiatus of the diaphragm, and the common hepatic vein without the caudal vena cava passed through the caval foramen. Although the lungs and heart were morphologically normal, the right atrium received three major systemic veins. Polysplenia syndrome was diagnosed based on the CT and postmortem findings. Conclusion We defined the positions of the abdominal organs and morphological abnormalities in various organs of a calf with polysplenia syndrome based on CT and postmortem findings. These findings will improve understanding of the malpositioning and malformations that can occur in the organs of cattle with polysplenia syndrome.http://link.springer.com/article/10.1186/s12917-017-1213-2CattleDuodenumDysplasiaHeterotaxyLaterality disorderMalposition |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daisuke Kondoh Tomomi Kawano Tomoaki Kikuchi Kaoru Hatate Kenichi Watanabe Motoki Sasaki Norio Yamagishi Hisashi Inokuma Nobuo Kitamura |
spellingShingle |
Daisuke Kondoh Tomomi Kawano Tomoaki Kikuchi Kaoru Hatate Kenichi Watanabe Motoki Sasaki Norio Yamagishi Hisashi Inokuma Nobuo Kitamura Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report BMC Veterinary Research Cattle Duodenum Dysplasia Heterotaxy Laterality disorder Malposition |
author_facet |
Daisuke Kondoh Tomomi Kawano Tomoaki Kikuchi Kaoru Hatate Kenichi Watanabe Motoki Sasaki Norio Yamagishi Hisashi Inokuma Nobuo Kitamura |
author_sort |
Daisuke Kondoh |
title |
Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report |
title_short |
Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report |
title_full |
Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report |
title_fullStr |
Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report |
title_full_unstemmed |
Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report |
title_sort |
polysplenia syndrome with duodenal and pancreatic dysplasia in a holstein calf: a case report |
publisher |
BMC |
series |
BMC Veterinary Research |
issn |
1746-6148 |
publishDate |
2017-09-01 |
description |
Abstract Background Laterality disorders of the abdominal organs include situs inversus totalis that mirrors the arrangements of all internal organs and heterotaxy syndrome (situs ambiguus) in which the thoracic or abdominal organs are abnormally arranged. Heterotaxy is often accompanied by multiple congenital malformations, and it generally comprises asplenia and polysplenia syndromes. To our knowledge, polysplenia syndrome has been reported in only three cattle, and computerized tomographic (CT) images of these animals were not obtained. Case presentation A six-month-old Holstein heifer had ruminal tympani and right abdominal distension. CT imaging showed that the rumen occupied the right side of the abdominal cavity, the omasum and abomasum occupied the left ventral side and the liver was positioned on the left. The colon and cecum were located at the left dorsum of the cavity, and the left kidney was located more cranially than the right. Postmortem findings revealed two spleens attached to the rumen. Significantly, the duodenum was too short to be divided into segments, except the cranial and descending parts, or flexures, except the cranial flexure, and the pancreas, which lacked a left lobe, was covered with mesojejunum. The liver comprised a relatively large right lobe and a small left lobe without quadrate and caudate lobes. The caudal vena cava that connected to the left azygous vein passed irregularly through the aortic hiatus of the diaphragm, and the common hepatic vein without the caudal vena cava passed through the caval foramen. Although the lungs and heart were morphologically normal, the right atrium received three major systemic veins. Polysplenia syndrome was diagnosed based on the CT and postmortem findings. Conclusion We defined the positions of the abdominal organs and morphological abnormalities in various organs of a calf with polysplenia syndrome based on CT and postmortem findings. These findings will improve understanding of the malpositioning and malformations that can occur in the organs of cattle with polysplenia syndrome. |
topic |
Cattle Duodenum Dysplasia Heterotaxy Laterality disorder Malposition |
url |
http://link.springer.com/article/10.1186/s12917-017-1213-2 |
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