Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient
Strongyloides stercoralis is a nematode, endemic in tropical and subtropical areas. Strongyloidiasis has been reported in recipients of hematopoietic stem cells, kidney, liver, heart, intestine, and pancreas, eventually presenting as disseminated strongyloidiasis and hyperinfection syndrome (SHS) wh...
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doaj-d0a15a54e2eb43dcadc1cc23daaa78332021-07-02T12:42:56ZengElsevierIDCases2214-25092020-01-0119Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipientAna Cipriano0Rita Dias1Ricardo Marinho2Sofia Correia3Virgínia Lopes4Teresa Cardoso5Irene Aragão6Infectious Disease Department, Centro Hospitalar do Porto, Portugal; Corresponding author at: Centro Hospitalar do Porto, Infectious Disease Department, Largo do Prof. Abel Salazar, 4099-001, Porto, Portugal.Internal Medicine Department, Centro Hospitalar do Porto, PortugalInternal Medicine Department, Centro Hospitalar do Porto, PortugalNephrology and Transplant Unit, Centro Hospitalar do Porto, PortugalClinical Microbiology Department, Centro Hospitalar do Porto, PortugalDepartment of Intensive Care Unit, Centro Hospitalar Porto, Porto, PortugalDepartment of Intensive Care Unit, Centro Hospitalar Porto, Porto, PortugalStrongyloides stercoralis is a nematode, endemic in tropical and subtropical areas. Strongyloidiasis has been reported in recipients of hematopoietic stem cells, kidney, liver, heart, intestine, and pancreas, eventually presenting as disseminated strongyloidiasis and hyperinfection syndrome (SHS) which is associated with high mortality. We report one case of a recent renal transplant recipient, who presented with gastrointestinal and respiratory symptoms, evolving into shock. The identification of Strongyloides stercoralis in the bronchoalveolar lavage (BAL) lead us to the diagnosis of SHS. Treatment with subcutaneous ivermectin was started, however the patient did not survive. Retrospective serum donor analysis allowed us to identify the donor as the source of infection. Keywords: Donor-derived infection, Strongyloides stercoralis, Strongyloides hyperinfection syndrome, Subcutaneus irvemectin, Kidney transplantationhttp://www.sciencedirect.com/science/article/pii/S2214250920300111 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ana Cipriano Rita Dias Ricardo Marinho Sofia Correia Virgínia Lopes Teresa Cardoso Irene Aragão |
spellingShingle |
Ana Cipriano Rita Dias Ricardo Marinho Sofia Correia Virgínia Lopes Teresa Cardoso Irene Aragão Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient IDCases |
author_facet |
Ana Cipriano Rita Dias Ricardo Marinho Sofia Correia Virgínia Lopes Teresa Cardoso Irene Aragão |
author_sort |
Ana Cipriano |
title |
Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient |
title_short |
Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient |
title_full |
Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient |
title_fullStr |
Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient |
title_full_unstemmed |
Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient |
title_sort |
donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient |
publisher |
Elsevier |
series |
IDCases |
issn |
2214-2509 |
publishDate |
2020-01-01 |
description |
Strongyloides stercoralis is a nematode, endemic in tropical and subtropical areas. Strongyloidiasis has been reported in recipients of hematopoietic stem cells, kidney, liver, heart, intestine, and pancreas, eventually presenting as disseminated strongyloidiasis and hyperinfection syndrome (SHS) which is associated with high mortality. We report one case of a recent renal transplant recipient, who presented with gastrointestinal and respiratory symptoms, evolving into shock. The identification of Strongyloides stercoralis in the bronchoalveolar lavage (BAL) lead us to the diagnosis of SHS. Treatment with subcutaneous ivermectin was started, however the patient did not survive. Retrospective serum donor analysis allowed us to identify the donor as the source of infection. Keywords: Donor-derived infection, Strongyloides stercoralis, Strongyloides hyperinfection syndrome, Subcutaneus irvemectin, Kidney transplantation |
url |
http://www.sciencedirect.com/science/article/pii/S2214250920300111 |
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