Effect of central obesity on lipid profile in healthy young adults

• Main Authors: Shaikat Mondal, Surajit Kumar Mukhopadhyay
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Medical Journal of Dr. D.Y. Patil Vidyapeeth
• Subjects: Abdominal obesity; cholesterol; lipid profile; visceral fat; waist-to-height ratio
• Online Access: http://www.mjdrdypv.org/article.asp?issn=2589-8302;year=2018;volume=11;issue=2;spage=152;epage=157;aulast=Mondal

Background: Increased abdominal obesity is related to adverse metabolic markers. Waist circumference (WC) alone has been shown to correlate more strongly to direct measures of abdominal fat accumulation. Waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) are other parameters to estimate abdominal obesity. Increase in total cholesterol (TC), and triglyceride (TG) increases health risks; whereas, decrease in high density lipoprotein cholesterol (HDL-C) increases future health risk. Aim: The aim of the present study was to find if any correlation exist between central obesity and serum lipid profile in otherwise healthy young adults. Materials and Methods: A cross-sectional study was conducted with 76 (male = 41, female = 35) apparently healthy young adults. Weight, height, WC, and hip circumference were measured. WHR and WHtR were calculated from measured parameters. Serum lipid profile parameters were obtained from venous blood collected after overnight fasting (i.e., 12 h fasting). Pearson's correlation (with α = 0.05) was used to obtain a correlation between central obesity parameters and lipid profile parameters. Statistical analyses were performed in GraphPad Prism 6.01 windows based software. Results: Mean age of the subjects was 18.83 ± 0.85 years. Correlation of WC with TC (r = 0.08, P = 0.45), TG (r = 0.21, P = 0.05) and HDL-C (r = −0.06, P = 0.56) was insignificant. Correlation of WHR with TC (r = 0.07, P = 0.49), TG (r = 0.26, P = 0.02) and HDL-C (r = 0.07, P = 0.50) and WHtR with TC (r = 0.09, P = 0.41), TG (r = 0.17, P = 0.12) and HDL-C (r = 0.03, P = 0.74) also showed insignificant correlation. Conclusion: Indirectly measured central obesity has an insignificant correlation with serum lipid profile in healthy young adults.