Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation
Growing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to maintain a healthy gut microbiota and overall wel...
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doaj-d0b95ae3e06a4b069db99fad4ffad5df2021-06-30T23:22:26ZengMDPI AGFoods2304-81582021-06-01101297129710.3390/foods10061297Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota ModulationMonika Kvakova0Izabela Bertkova1Jana Stofilova2Tor C. Savidge3Department of Experimental Medicine, Faculty of Medicine, P.J. Safarik University in Kosice, Trieda SNP 1, 04011 Kosice, SlovakiaDepartment of Experimental Medicine, Faculty of Medicine, P.J. Safarik University in Kosice, Trieda SNP 1, 04011 Kosice, SlovakiaDepartment of Experimental Medicine, Faculty of Medicine, P.J. Safarik University in Kosice, Trieda SNP 1, 04011 Kosice, SlovakiaDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USAGrowing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to maintain a healthy gut microbiota and overall well-being, is undeniable and inevitable. This review focuses on the modern approaches that are currently being developed to modulate the gut microbiota, with an emphasis on the health benefits mediated by co-encapsulated synbiotics and immobilized probiotics. The impact of processing, storage, and simulated gastrointestinal conditions on the viability and bioactivity of probiotics together with prebiotics such as omega-3 polyunsaturated fatty acids, phytochemicals, and dietary fibers using various delivery systems are considered. Despite the proven biological properties of synbiotics, research in this area needs to be focused on the proper selection of probiotic strains, their prebiotic counterparts, and delivery systems to avoid suppression of their synergistic or complementary effect on human health. Future directions should lead to the development of functional food products containing stable synbiotics tailored for different age groups or specifically designed to fulfill the needs of adjuvant therapy.https://www.mdpi.com/2304-8158/10/6/1297co-encapsulated synbioticsimmobilized probioticsprebioticssynergismgut microbiota modulationhealth benefits |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Monika Kvakova Izabela Bertkova Jana Stofilova Tor C. Savidge |
spellingShingle |
Monika Kvakova Izabela Bertkova Jana Stofilova Tor C. Savidge Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation Foods co-encapsulated synbiotics immobilized probiotics prebiotics synergism gut microbiota modulation health benefits |
author_facet |
Monika Kvakova Izabela Bertkova Jana Stofilova Tor C. Savidge |
author_sort |
Monika Kvakova |
title |
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation |
title_short |
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation |
title_full |
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation |
title_fullStr |
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation |
title_full_unstemmed |
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation |
title_sort |
co-encapsulated synbiotics and immobilized probiotics in human health and gut microbiota modulation |
publisher |
MDPI AG |
series |
Foods |
issn |
2304-8158 |
publishDate |
2021-06-01 |
description |
Growing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to maintain a healthy gut microbiota and overall well-being, is undeniable and inevitable. This review focuses on the modern approaches that are currently being developed to modulate the gut microbiota, with an emphasis on the health benefits mediated by co-encapsulated synbiotics and immobilized probiotics. The impact of processing, storage, and simulated gastrointestinal conditions on the viability and bioactivity of probiotics together with prebiotics such as omega-3 polyunsaturated fatty acids, phytochemicals, and dietary fibers using various delivery systems are considered. Despite the proven biological properties of synbiotics, research in this area needs to be focused on the proper selection of probiotic strains, their prebiotic counterparts, and delivery systems to avoid suppression of their synergistic or complementary effect on human health. Future directions should lead to the development of functional food products containing stable synbiotics tailored for different age groups or specifically designed to fulfill the needs of adjuvant therapy. |
topic |
co-encapsulated synbiotics immobilized probiotics prebiotics synergism gut microbiota modulation health benefits |
url |
https://www.mdpi.com/2304-8158/10/6/1297 |
work_keys_str_mv |
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