Biopathological Significance of PIWI–piRNA Pathway Deregulation in Invasive Breast Carcinomas

Biopathological Significance of PIWI–piRNA Pathway Deregulation in Invasive Breast Carcinomas

The PIWI proteins emerging in the development of human cancers, edify PIWI-piRNA ribonucleoproteic complexes acting as pivotal regulators of genome integrity, differentiation and homeostasis. The aim of this study is to analyze the four PIWILs gene expression in invasive breast carcinomas (IBCs): at...

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Bibliographic Details
Main Authors: Didier Meseure, Sophie Vacher, Sabah Boudjemaa, Marick Laé, André Nicolas, Renaud Leclere, Walid Chemlali, Gabriel Champenois, Anne Schnitzler, Laetitia Lesage, Thierry Dubois, Ivan Bieche
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
piRNA
PIWI proteins
transposable elements
silencing
methylation
heterochromatin
Online Access:https://www.mdpi.com/2072-6694/12/10/2833

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