Vascular effects of quinapril completely depend on ACE insertion/deletion polymorphism

Introduction The angiotensin-converting enzyme (ACE) DD-genotype is associated with increased plasma and myocardial ACE-activity. The influence of the ACE insertion/deletion (I/D) polymorphism on the effects of ACE-inhibition on vascular responses has not been previously described. Materials and met...

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Bibliographic Details
Main Authors: Adriaan A Voors, Peter P van Geel, Margreeth Oosterga, Hendrik Buikema, Dirk J van Veldhuisen, Wiek H van Gilst
Format: Article
Published: Hindawi - SAGE Publishing 2004-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
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