STAT1 Is Required for Decreasing Accumulation of Granulocytic Cells via IL-17 during Initial Steps of Colitis-Associated Cancer

STAT1 Is Required for Decreasing Accumulation of Granulocytic Cells via IL-17 during Initial Steps of Colitis-Associated Cancer

Signal transducer and activator of transcription 1 (STAT1) acts as a tumor suppressor molecule in colitis-associated colorectal cancer (CAC), particularly during the very early stages, modulating immune responses and controlling mechanisms such as apoptosis and cell proliferation. Previously, using...

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Bibliographic Details
Main Authors: Yael Delgado-Ramirez, Itzel Baltazar-Perez, Yamileth Martinez, Blanca E. Callejas, Itzel Medina-Andrade, Jonadab E. Olguín, Norma L. Delgado-Buenrostro, Yolanda I. Chirino, Luis I. Terrazas, Sonia Leon-Cabrera
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
colitis-associated cancer
STAT1
IL-17
MDSCs
Online Access:https://www.mdpi.com/1422-0067/22/14/7695

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