Genetically Obese Human Gut Microbiota Induces Liver Steatosis in Germ-Free Mice Fed on Normal Diet

Genetically Obese Human Gut Microbiota Induces Liver Steatosis in Germ-Free Mice Fed on Normal Diet

Dysbiotic gut microbiota contributes to genetically obese phenotype in human. However, the effect of genetic obesity-associated gut microbiota on host hepatic metabolic deteriorations remains largely unknown. Gut microbiota from a genetically obese human donor before and after a dietary weight loss...

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Bibliographic Details
Main Authors: Ruirui Wang, Hui Li, Xin Yang, Xinhe Xue, Liman Deng, Jian Shen, Menghui Zhang, Liping Zhao, Chenhong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
gut microbiota
genetic obesity
germ-free mice
liver steatosis
hepatic lipid metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01602/full

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