Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates

Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates

Abstract Background Competitive outcomes between co-infecting malaria parasite lines can reveal fitness disparities in blood stage growth. Blood stage fitness costs often accompany the evolution of drug resistance, with the expectation that relatively fitter parasites will be more likely to spread i...

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Bibliographic Details
Main Authors: Abigail R. Tirrell, Katelyn M. Vendrely, Lisa A. Checkley, Sage Z. Davis, Marina McDew-White, Ian H. Cheeseman, Ashley M. Vaughan, François H. Nosten, Timothy J. C. Anderson, Michael T. Ferdig
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Malaria Journal
Subjects:
Competitive growth
Fitness
Artemisinin resistance
kelch13
Population genetics
Online Access:http://link.springer.com/article/10.1186/s12936-019-2934-4

Internet

http://link.springer.com/article/10.1186/s12936-019-2934-4

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