BclI polymorphism of the glucocorticoid receptor and adrenal crisis in primary adrenal insufficiency

BclI polymorphism of the glucocorticoid receptor and adrenal crisis in primary adrenal insufficiency

Context: Patients with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) are at a high risk of adrenal crisis (AC). Glucocorticoid sensitivity is at least partially genetically determined by polymorphisms of the glucocorticoid receptor (GR). Objectives: To determine if a n...

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Bibliographic Details
Main Authors: Kathrin Zopf, Kathrin R Frey, Tina Kienitz, Manfred Ventz, Britta Bauer, Marcus Quinkler
Format: Article
Language:English
Published: Bioscientifica 2017-10-01
Series:Endocrine Connections
Subjects:
adrenal insufficiency
adrenal crisis
cortisol
hydrocortisone
polyglandular autoimmune syndrome
Online Access:http://www.endocrineconnections.com/content/6/8/685.full

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