Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia

Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia

Intermittent hypoxia (IH) is associated with increased endothelial dysfunction and cardiovascular disorders. Exosomes released in biological fluids may act as vehicles for propagating such damage, modifying the functional phenotype of endothelial cells. Drug interventions, however, may provide prote...

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Bibliographic Details
Main Authors: Abdelnaby Khalyfa, Nina Youssefnia, Glen E. Foster, Andrew E. Beaudin, Zhuanghong Qiao, Vincent Pialoux, Matiram Pun, Patrick J. Hanly, Leila Kheirandish-Gozal, Marc J. Poulin, David Gozal
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Neurology
Subjects:
cardiovascular disease
intermittent hypoxia
sleep apnea
experimental human model
endothelium
exosomes
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00709/full

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