Nonproteolytic K29-Linked Ubiquitination of the PB2 Replication Protein of Influenza A Viruses by Proviral Cullin 4-Based E3 Ligases

Nonproteolytic K29-Linked Ubiquitination of the PB2 Replication Protein of Influenza A Viruses by Proviral Cullin 4-Based E3 Ligases

Successful infection by influenza A virus, a pathogen of major public health importance, involves fine regulation of the multiple functions of the viral proteins, which often relies on post-translational modifications (PTMs). The PB2 protein of influenza A viruses is essential for viral replication...

Full description

Bibliographic Details
Main Authors: Marwah Karim, Elise Biquand, Marion Declercq, Yves Jacob, Sylvie van der Werf, Caroline Demeret
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
k29-linked ubiquitination
pb2 replication protein
cullin-based e3 ligases
influenza virus
nonproteolytic ubiquitination
post-translational modification
ubiquitination
Online Access:https://doi.org/10.1128/mBio.00305-20

Similar Items

Similar Items