Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations

The aim of this study was the optimization of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in terms of physicochemical and biopharmaceutical properties, to develop effective and stable aqueous liquid formulations of hydrochlorothiazide, suitable for paediatric therapy, ove...

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Bibliographic Details
Main Authors: Paola Mura, Francesca Maestrelli, Mario D’Ambrosio, Cristina Luceri, Marzia Cirri
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
solid lipid nanoparticles
nanostructured lipid carriers
hydrochlorothiazide
pediatric therapy
Gelucire
cytotoxicity
Online Access:https://www.mdpi.com/1999-4923/13/4/437

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https://www.mdpi.com/1999-4923/13/4/437

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