Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique
AIM: To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH). METHODS: This study was a prospective noncontrolled interventional study. All patients were treated...
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doaj-d127e1c21a484e11a5d1b7761f2dc4532020-11-24T21:52:12ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982019-02-0112224625110.18240/ijo.2019.02.10Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap techniqueLi-Ping Wang0Wen-Tao Sun1Chun-Ling Lei2Jin Deng3Department of Ophthalmology, Shaanxi Ophthalmic Medical Center, Xi’an Fourth Hospital, Affiliated Guangren Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Ophthalmology, Shaanxi Ophthalmic Medical Center, Xi’an Fourth Hospital, Affiliated Guangren Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Ophthalmology, Shaanxi Ophthalmic Medical Center, Xi’an Fourth Hospital, Affiliated Guangren Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Ophthalmology, Shaanxi Ophthalmic Medical Center, Xi’an Fourth Hospital, Affiliated Guangren Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaAIM: To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH). METHODS: This study was a prospective noncontrolled interventional study. All patients were treated by vitrectomy, the tiled transplantation ILM pedicle flap and gas tamponade. All patients underwent visual acuity measurements and optical coherence tomography (OCT), during preoperative and the follow-up visits postoperative. RESULTS: Two high-myopic patient had flap dislocation during surgery. The thorough closure of MH following the tiled transplantation ILM pedicle flap technique was ultimately achieved in 31 patients observed by OCT imaging (93.94%) 1wk after surgery. Visual acuity improved from 1.51±0.31 (logMAR) preoperative to 0.92±0.30 6mo after surgery (P=0.000). There were no significant changes in OCT finding during the follow-up period from 1mo to 6mo after surgery. CONCLUSION: The tiled transplantation ILM pedicle flap technique provides bridge for retinal gliosis to achieve successful closures of the large MHs, and the microenvironment of this technique is more similar to the normal physiological conditions.http://www.ijo.cn/en_publish/2019/2/20190210.pdftiled transplantation ilm pedicle flapmacular holevitrectomy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Li-Ping Wang Wen-Tao Sun Chun-Ling Lei Jin Deng |
spellingShingle |
Li-Ping Wang Wen-Tao Sun Chun-Ling Lei Jin Deng Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique International Journal of Ophthalmology tiled transplantation ilm pedicle flap macular hole vitrectomy |
author_facet |
Li-Ping Wang Wen-Tao Sun Chun-Ling Lei Jin Deng |
author_sort |
Li-Ping Wang |
title |
Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique |
title_short |
Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique |
title_full |
Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique |
title_fullStr |
Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique |
title_full_unstemmed |
Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique |
title_sort |
clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2019-02-01 |
description |
AIM: To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH).
METHODS: This study was a prospective noncontrolled interventional study. All patients were treated by vitrectomy, the tiled transplantation ILM pedicle flap and gas tamponade. All patients underwent visual acuity measurements and optical coherence tomography (OCT), during preoperative and the follow-up visits postoperative.
RESULTS: Two high-myopic patient had flap dislocation during surgery. The thorough closure of MH following the tiled transplantation ILM pedicle flap technique was ultimately achieved in 31 patients observed by OCT imaging (93.94%) 1wk after surgery. Visual acuity improved from 1.51±0.31 (logMAR) preoperative to 0.92±0.30 6mo after surgery (P=0.000). There were no significant changes in OCT finding during the follow-up period from 1mo to 6mo after surgery.
CONCLUSION: The tiled transplantation ILM pedicle flap technique provides bridge for retinal gliosis to achieve successful closures of the large MHs, and the microenvironment of this technique is more similar to the normal physiological conditions. |
topic |
tiled transplantation ilm pedicle flap macular hole vitrectomy |
url |
http://www.ijo.cn/en_publish/2019/2/20190210.pdf |
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