Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development
Muscle stem cells (MuSCs) exhibit distinct behavior during successive phases of developmental myogenesis. However, how their transition to adulthood is regulated is poorly understood. Here, we show that fetal MuSCs resist progenitor specification and exhibit altered division dynamics, intrinsic feat...
Main Authors: | Matthew Timothy Tierney, Anastasia Gromova, Francesca Boscolo Sesillo, David Sala, Caroline Spenlé, Gertraud Orend, Alessandra Sacco |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716300651 |
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