Feasibility of quantifying SDC2 methylation in stool DNA for early detection of colorectal cancer

Feasibility of quantifying SDC2 methylation in stool DNA for early detection of colorectal cancer

Abstract Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected genes and early during CRC development, which has emerged as a new epigenetic biomarker for early detection of CRC...

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Bibliographic Details
Main Authors: Tae Jeong Oh, Hyun Il Oh, Yang Yei Seo, Dongjun Jeong, Changjin Kim, Hyoun Woo Kang, Yoon Dae Han, Hyun Cheol Chung, Nam Kyu Kim, Sungwhan An
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Clinical Epigenetics
Subjects:
Colorectal cancer
Early detection
Methylation
Precancerous lesion
SDC2
Stool DNA
Online Access:http://link.springer.com/article/10.1186/s13148-017-0426-3

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