Validation of the Finnish diabetes risk score (FINDRISC) for the Caucasian population of Siberia

• Main Authors: Svetlana V. Mustafina, Oksana D. Rymar, Olga V. Sazonova, Liliya V. Shcherbakova, Michail I. Voevoda
• Format: Article
• Language: English
• Published: Endocrinology Research Centre 2016-04-01
• Series: Сахарный диабет
• Subjects: validation; type 2 diabetes; risk factors; risk score; findrisc
• Online Access: https://dia-endojournals.ru/dia/article/viewFile/7630/5736

Aim. A validation of the Finnish diabetes risk score (FINDRISC) was conducted among the Siberian population. FINDRISC was used to study the prevalence of risk factors for type 2 diabetes mellitus (T2DM) and to estimate the incidence of T2DM in high-risk groups during a 10-year observation period.  Materials and methods. A total of 9,360 subjects aged between 45 and 69 years were enrolled in this cross-sectional, population-based study. FINDRISC was used to group 8,050 people without diabetes according to their risk for T2DM. Statistical analysis was performed using SPSS.  Results. When a cutoff point of 11 was used to identify those with diabetes, sensitivity was 76. 0% and specificity was 60. 2%. The area under the receiver operating curve for diabetes was 0. 73 (0. 73 for men and 0. 70 for women). More than one-third (31. 7%) of the adult population of Novosibirsk was estimated to have medium, high or very high risk of developing T2DM in the next 10 years. Cases of T2DM estimated to occur during the 10 years of follow-up had significantly higher incidence of risk factors such as BMI ≥30 kg/m2, waist circumference 102 cm in men and 88 cm in women and a family history of T2DM and were more likely to take drugs to lower blood pressure.  Conclusion. FINDRISC provided good results in our sample, and we recommend its use in the Siberian population.