Lymphoid EVA1 expression is required for DN1-DN3 thymocytes transition.

BACKGROUND:Thymus organogenesis and T lymphocyte development are accomplished together during fetal life. Proper development and maintenance of thymus architecture depend on signals generated by a sustained crosstalk between developing thymocytes and stromal elements. Any maturation impairment occur...

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Bibliographic Details
Main Authors: Stefano Iacovelli, Ilaria Iosue, Silvia Di Cesare, Maria Guttinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2761490?pdf=render