Visceral adiposity index is associated with lung function impairment: a population-based study
Abstract Background The effects of visceral adiposity on decreased lung function have drawn much attention. Recently, the visceral adiposity index (VAI) has been proposed as a visceral fat distribution and dysfunction marker. However, the relationship between the VAI and lung function has not been i...
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doaj-d16192f4289f44bcbc217f3a18d12e0c2021-01-10T12:25:13ZengBMCRespiratory Research1465-993X2021-01-012211910.1186/s12931-020-01599-3Visceral adiposity index is associated with lung function impairment: a population-based studySunyue He0Jie Yang1Xiaoyong Li2Hongxia Gu3Qing Su4Li Qin5Department of Endocrinology, Xinhua Hospital Chongming Branch, School of Medicine, Shanghai Jiaotong UniversityDepartment of Endocrinology, Xinhua Hospital Chongming Branch, School of Medicine, Shanghai Jiaotong UniversityDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Endocrinology, Xinhua Hospital Chongming Branch, School of Medicine, Shanghai Jiaotong UniversityDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Endocrinology, Xinhua Hospital Chongming Branch, School of Medicine, Shanghai Jiaotong UniversityAbstract Background The effects of visceral adiposity on decreased lung function have drawn much attention. Recently, the visceral adiposity index (VAI) has been proposed as a visceral fat distribution and dysfunction marker. However, the relationship between the VAI and lung function has not been investigated. The objective of the study was to analyze the association between the VAI and lung function and evaluate the potential of VAI as a predictor of lung function. Methods We collected data from a population-based study of 1786 subjects aged 40 years or older. All subjects completed a questionnaire and underwent anthropometric measurements and laboratory tests. Linear and logistic regression models were developed to assess the association between the VAI and lung function. Results The VAI was inversely related to FVC%predicted in men and negatively associated with both FVC%predicted and FEV1%predicted in women. In the linear regression analysis, the decrease in FVC%predicted associated with each 10% increase in the VAI was 1.127% in men and 1.943% in women; the decrease in FEV1%predicted associated with each 10%increase in the VAI was 0.663% in men and 1.738% in women. Further regression analysis revealed that the VAI was positively correlated with FVC and FEV1 impairment in women. Conclusions We were the first to show a clear correlation between the VAI and lung function impairment in the Chinese population. The VAI could be a simple and reliable approach in daily practice, and individuals, especially women with a high VAI, should receive additional screening and preventive interventions for respiratory disease.https://doi.org/10.1186/s12931-020-01599-3Lung functionVisceral adiposity indexVisceral adiposity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sunyue He Jie Yang Xiaoyong Li Hongxia Gu Qing Su Li Qin |
spellingShingle |
Sunyue He Jie Yang Xiaoyong Li Hongxia Gu Qing Su Li Qin Visceral adiposity index is associated with lung function impairment: a population-based study Respiratory Research Lung function Visceral adiposity index Visceral adiposity |
author_facet |
Sunyue He Jie Yang Xiaoyong Li Hongxia Gu Qing Su Li Qin |
author_sort |
Sunyue He |
title |
Visceral adiposity index is associated with lung function impairment: a population-based study |
title_short |
Visceral adiposity index is associated with lung function impairment: a population-based study |
title_full |
Visceral adiposity index is associated with lung function impairment: a population-based study |
title_fullStr |
Visceral adiposity index is associated with lung function impairment: a population-based study |
title_full_unstemmed |
Visceral adiposity index is associated with lung function impairment: a population-based study |
title_sort |
visceral adiposity index is associated with lung function impairment: a population-based study |
publisher |
BMC |
series |
Respiratory Research |
issn |
1465-993X |
publishDate |
2021-01-01 |
description |
Abstract Background The effects of visceral adiposity on decreased lung function have drawn much attention. Recently, the visceral adiposity index (VAI) has been proposed as a visceral fat distribution and dysfunction marker. However, the relationship between the VAI and lung function has not been investigated. The objective of the study was to analyze the association between the VAI and lung function and evaluate the potential of VAI as a predictor of lung function. Methods We collected data from a population-based study of 1786 subjects aged 40 years or older. All subjects completed a questionnaire and underwent anthropometric measurements and laboratory tests. Linear and logistic regression models were developed to assess the association between the VAI and lung function. Results The VAI was inversely related to FVC%predicted in men and negatively associated with both FVC%predicted and FEV1%predicted in women. In the linear regression analysis, the decrease in FVC%predicted associated with each 10% increase in the VAI was 1.127% in men and 1.943% in women; the decrease in FEV1%predicted associated with each 10%increase in the VAI was 0.663% in men and 1.738% in women. Further regression analysis revealed that the VAI was positively correlated with FVC and FEV1 impairment in women. Conclusions We were the first to show a clear correlation between the VAI and lung function impairment in the Chinese population. The VAI could be a simple and reliable approach in daily practice, and individuals, especially women with a high VAI, should receive additional screening and preventive interventions for respiratory disease. |
topic |
Lung function Visceral adiposity index Visceral adiposity |
url |
https://doi.org/10.1186/s12931-020-01599-3 |
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