Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis.

Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis.

Spleen stromal lines which support in vitro hematopoiesis are investigated for their lineage origin and hematopoietic support function in vivo. Marker expression and gene profiling identify a lineage relationship with mesenchymal stem cells and perivascular reticular cells described recently in bone...

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Bibliographic Details
Main Authors: Helen C O'Neill, Hong K Lim, Pravin Periasamy, Lavanya Kumarappan, Jonathan K H Tan, Terence J O'Neill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223416

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