STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and provide a mechanism for its requirement in antige...
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Bibliographic Details
Main Authors: |
Paula Nunes-Hasler,
Sophia Maschalidi,
Carla Lippens,
Cyril Castelbou,
Samuel Bouvet,
Daniele Guido,
Flavien Bermont,
Esen Y. Bassoy,
Nicolas Page,
Doron Merkler,
Stéphanie Hugues,
Denis Martinvalet,
Bénédicte Manoury,
Nicolas Demaurex |
Format: | Article
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Language: | English |
Published: |
Nature Publishing Group
2017-11-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-017-01600-6
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