Focused Ultrasound Ablation of an Arteriovenous Malformation Model

Focused Ultrasound Ablation of an Arteriovenous Malformation Model

Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one...

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Bibliographic Details
Main Authors: Jesse Jones, Mark Bolding, Henrik Ullman, Naoki Kaneko, Satoshi Tateshima
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neurology
Subjects:
arteriovenous malformation
embolization
high intensity focus ultrasound
non-invasive ablation
MRI guided ablation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.671380/full
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spelling doaj-d19736538cb0414da9a8bf3fd2ff54232021-06-03T04:57:47ZengFrontiers Media S.A.Frontiers in Neurology1664-22952021-06-011210.3389/fneur.2021.671380671380Focused Ultrasound Ablation of an Arteriovenous Malformation ModelJesse Jones0Mark Bolding1Henrik Ullman2Naoki Kaneko3Satoshi Tateshima4Departments of Neurosurgery and Radiology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Radiology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Radiology, School of Medicine, University of California, Los Angeles, Los Angeles, CA, United StatesDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United StatesDepartment of Radiology, School of Medicine, University of California, Los Angeles, Los Angeles, CA, United StatesBrain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile.https://www.frontiersin.org/articles/10.3389/fneur.2021.671380/fullarteriovenous malformationembolizationhigh intensity focus ultrasoundnon-invasive ablationMRI guided ablation
collection DOAJ
language English
format Article
sources DOAJ
author Jesse Jones
Mark Bolding
Henrik Ullman
Naoki Kaneko
Satoshi Tateshima
spellingShingle Jesse Jones
Mark Bolding
Henrik Ullman
Naoki Kaneko
Satoshi Tateshima
Focused Ultrasound Ablation of an Arteriovenous Malformation Model
Frontiers in Neurology
arteriovenous malformation
embolization
high intensity focus ultrasound
non-invasive ablation
MRI guided ablation
author_facet Jesse Jones
Mark Bolding
Henrik Ullman
Naoki Kaneko
Satoshi Tateshima
author_sort Jesse Jones
title Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_short Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_full Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_fullStr Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_full_unstemmed Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_sort focused ultrasound ablation of an arteriovenous malformation model
publisher Frontiers Media S.A.
series Frontiers in Neurology
issn 1664-2295
publishDate 2021-06-01
description Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile.
topic arteriovenous malformation
embolization
high intensity focus ultrasound
non-invasive ablation
MRI guided ablation
url https://www.frontiersin.org/articles/10.3389/fneur.2021.671380/full
work_keys_str_mv AT jessejones focusedultrasoundablationofanarteriovenousmalformationmodel
AT markbolding focusedultrasoundablationofanarteriovenousmalformationmodel
AT henrikullman focusedultrasoundablationofanarteriovenousmalformationmodel
AT naokikaneko focusedultrasoundablationofanarteriovenousmalformationmodel
AT satoshitateshima focusedultrasoundablationofanarteriovenousmalformationmodel
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