| Summary: | <strong>Foundation:</strong> there is an undervaluing of what lipidemia means as a sign of a health problem in individuals who go to donate blood.<strong> <br />Objective:</strong> to estimate the prevalence of risk factors for cardiovascular diseases and to measure its association with the presence of lipidemia in blood donors. <br /><strong>Methods:</strong> a descriptive analytic study of cases and controls with 33 and 66 patients respectivelyat the Cienfuegos Provincial Blood Bank, from March 1st to October 31st 2015. Cases were identified as positive at the pre-donating lipidemia test and the controls with negative test. The variables considered were: suitable and not suitable donors, lipidemia, age, smoking habit, diabetes mellitus, high blood pressure, abdominal waist, body mass index, triglycerides, total cholesterol and their fractions. It was calculated the Pearson correlation coefficient to measure the association among variables with a confidence interval of 95%, Squared Chi X2 and Odds Ratio. <br /><strong>Results:</strong> lipidemia represented 30 % of the refusal causes in blood donors.The main risk factors found were decreased lipoproteins of low density, increased lipoproteins of low density obesity, hypertriglyceridemia, smoking habit and high blood pressure. The variables with higher values in Odd Ratios were triglycerides, abdominal waist, lipoproteins of low cholesterol level, abdominal waist and body mass index. <br /><strong>Conclusion:</strong>donors with turbid plasma have a more favorable cardiometabolic profile to suffer from cardiovascular diseases than those with negative lipidemia
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