Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility
Hereditary breast and ovarian cancer syndrome (HBOC) represents 5–10% of all patients with breast cancer and is associated with high-risk pathogenic alleles in BRCA1/2 genes, but only for 25% of cases. We aimed to find new pathogenic alleles in a panel of 143 cancer-predisposing genes in 300 Mexican...
Main Authors: | Rosalía Quezada Urban, Clara Estela Díaz Velásquez, Rina Gitler, María Patricia Rojo Castillo, Max Sirota Toporek, Andrea Figueroa Morales, Oscar Moreno García, Lizbeth García Esquivel, Gabriela Torres Mejía, Michael Dean, Iván Delgado Enciso, Héctor Ochoa Díaz López, Fernando Rodríguez León, Virginia Jan, Víctor Hugo Garzón Barrientos, Pablo Ruiz Flores, Perla Karina Espino Silva, Jorge Haro Santa Cruz, Héctor Martínez Gregorio, Ernesto Arturo Rojas Jiménez, Luis Enrique Romero Cruz, Claudia Fabiola Méndez Catalá, Rosa María Álvarez Gómez, Verónica Fragoso Ontiveros, Luis Alonso Herrera, Isabelle Romieu, Luis Ignacio Terrazas, Yolanda Irasema Chirino, Cecilia Frecha, Javier Oliver, Sandra Perdomo, Felipe Vaca Paniagua |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-09-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/10/361 |
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