Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment
<p>Analytical techniques based on <sup>19</sup>F NMR spectroscopy and HPLC-suppressed conductivity detection were developed to detect and quantify aqueous perfluoroctane sulfonate (PFOS), perfluoroctanoic acid (PFOA), and perfluorobutane sulfonate (PFBS). Chromatographic separation...
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Universidad San Francisco de Quito
2011-12-01
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doaj-d1c2947c425f47b285fe0d9840e7a09f2021-10-02T17:26:42ZengUniversidad San Francisco de QuitoACI Avances en Ciencias e Ingenierías1390-53842528-77882011-12-013210.18272/aci.v3i2.6363Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the EnvironmentValeria de Lourdes Ochoa-Herrera0Jim A. Field1Reyes Sierra-Alvarez2Universidad San Francisco de QuitoUniversity of ArizonaUniversity of Arizona<p>Analytical techniques based on <sup>19</sup>F NMR spectroscopy and HPLC-suppressed conductivity detection were developed to detect and quantify aqueous perfluoroctane sulfonate (PFOS), perfluoroctanoic acid (PFOA), and perfluorobutane sulfonate (PFBS). Chromatographic separation of the perfluoroalkyl surfactants (PFAS) was performed using a C<sup>18</sup> reversed-phase column and a mobile phase consisting of a mixture of boric acid and acetonitrile. The detection limit for PFOS by <sup>19</sup>F NMR was 3.6 mg L<sup>-1</sup>. The detection limit for PFOS, PFOA and PFBS by HPLC-suppressed conductivity detection was 1 mg L<sup>-1</sup>. The detection limits were shown to improve considerably if samples were pre-concentrated by solid-phase extraction. The detection limits for PFOS of pre-concentrated samples were 3.6 mg L<sup>-1</sup> and 10 ug L<sup>-1</sup> by <sup>19</sup>F NMR and HPLC-suppressed conductivity detection, respectively. Comparison of these two methodologies showed that HPLC-suppressed conductivity detection should be preferred for routine quantification of these contaminants due to its simplicity, time efficiency, and accuracy. Conversely, <sup>19</sup>F NMR can be used to characterize changes in the chemical structure of fluorinated compounds due to its inherent advantage of high specificity and no matrix interferences. The feasibility of utilizing total organic carbon (TOC) and chemical oxygen demand (COD) analysis for the quantitative detection of PFOS in aqueous samples was also investigated. Although, the TOC analysis provided reliable quantification of PFAS in aqueous samples, the non-specificity is a drawback of the technique. The dichromate-based COD method was found unsuitable for the analysis of PFOS due to the incomplete oxidation of the highly stable perfluorinated compound under the conditions evaluated.</p>http://revistas.usfq.edu.ec/index.php/avances/article/view/63PFASPFOSPFOAPFBS19F NMRHPLCdetector de conductividad suprimidaTOC and COD |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Valeria de Lourdes Ochoa-Herrera Jim A. Field Reyes Sierra-Alvarez |
spellingShingle |
Valeria de Lourdes Ochoa-Herrera Jim A. Field Reyes Sierra-Alvarez Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment ACI Avances en Ciencias e Ingenierías PFAS PFOS PFOA PFBS 19F NMR HPLC detector de conductividad suprimida TOC and COD |
author_facet |
Valeria de Lourdes Ochoa-Herrera Jim A. Field Reyes Sierra-Alvarez |
author_sort |
Valeria de Lourdes Ochoa-Herrera |
title |
Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment |
title_short |
Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment |
title_full |
Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment |
title_fullStr |
Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment |
title_full_unstemmed |
Development of Analytical Methods to Quantify Perfluorooctane Sulfonate and Related Compounds in the Environment |
title_sort |
development of analytical methods to quantify perfluorooctane sulfonate and related compounds in the environment |
publisher |
Universidad San Francisco de Quito |
series |
ACI Avances en Ciencias e Ingenierías |
issn |
1390-5384 2528-7788 |
publishDate |
2011-12-01 |
description |
<p>Analytical techniques based on <sup>19</sup>F NMR spectroscopy and HPLC-suppressed conductivity detection were developed to detect and quantify aqueous perfluoroctane sulfonate (PFOS), perfluoroctanoic acid (PFOA), and perfluorobutane sulfonate (PFBS). Chromatographic separation of the perfluoroalkyl surfactants (PFAS) was performed using a C<sup>18</sup> reversed-phase column and a mobile phase consisting of a mixture of boric acid and acetonitrile. The detection limit for PFOS by <sup>19</sup>F NMR was 3.6 mg L<sup>-1</sup>. The detection limit for PFOS, PFOA and PFBS by HPLC-suppressed conductivity detection was 1 mg L<sup>-1</sup>. The detection limits were shown to improve considerably if samples were pre-concentrated by solid-phase extraction. The detection limits for PFOS of pre-concentrated samples were 3.6 mg L<sup>-1</sup> and 10 ug L<sup>-1</sup> by <sup>19</sup>F NMR and HPLC-suppressed conductivity detection, respectively. Comparison of these two methodologies showed that HPLC-suppressed conductivity detection should be preferred for routine quantification of these contaminants due to its simplicity, time efficiency, and accuracy. Conversely, <sup>19</sup>F NMR can be used to characterize changes in the chemical structure of fluorinated compounds due to its inherent advantage of high specificity and no matrix interferences. The feasibility of utilizing total organic carbon (TOC) and chemical oxygen demand (COD) analysis for the quantitative detection of PFOS in aqueous samples was also investigated. Although, the TOC analysis provided reliable quantification of PFAS in aqueous samples, the non-specificity is a drawback of the technique. The dichromate-based COD method was found unsuitable for the analysis of PFOS due to the incomplete oxidation of the highly stable perfluorinated compound under the conditions evaluated.</p> |
topic |
PFAS PFOS PFOA PFBS 19F NMR HPLC detector de conductividad suprimida TOC and COD |
url |
http://revistas.usfq.edu.ec/index.php/avances/article/view/63 |
work_keys_str_mv |
AT valeriadelourdesochoaherrera developmentofanalyticalmethodstoquantifyperfluorooctanesulfonateandrelatedcompoundsintheenvironment AT jimafield developmentofanalyticalmethodstoquantifyperfluorooctanesulfonateandrelatedcompoundsintheenvironment AT reyessierraalvarez developmentofanalyticalmethodstoquantifyperfluorooctanesulfonateandrelatedcompoundsintheenvironment |
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