The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy

The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy

Globally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is linked to the rise in obesity rates among women of reproductive age. GDM poses a major global health problem due to the related micro- and macro-vascular complications of subsequent Type 2 diabetes and the impac...

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Main Authors: Delia Bogdanet, Paula O’Shea, Claire Lyons, Amir Shafat, Fidelma Dunne
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Clinical Medicine
Subjects:
oral glucose tolerance test
reproducibility
diabetes
gestational diabetes
Online Access:https://www.mdpi.com/2077-0383/9/11/3451
id doaj-d1c4fae319da4f5b97d74650320a9761
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spelling doaj-d1c4fae319da4f5b97d74650320a97612020-11-25T01:43:01ZengMDPI AGJournal of Clinical Medicine2077-03832020-10-0193451345110.3390/jcm9113451The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on PregnancyDelia Bogdanet0Paula O’Shea1Claire Lyons2Amir Shafat3Fidelma Dunne4Department of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, IrelandDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, IrelandDepartment of Clinical Biochemistry, SUHCG, University Hospital Galway, H91YR71 Galway, IrelandDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, IrelandDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, IrelandGlobally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is linked to the rise in obesity rates among women of reproductive age. GDM poses a major global health problem due to the related micro- and macro-vascular complications of subsequent Type 2 diabetes and the impact on the future health of generations through the long-term impact of GDM on both mothers and their infants. Therefore, correctly identifying subjects as having GDM is of utmost importance. The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing gestational diabetes for decades. However, this test is deeply flawed. In this review, we explore a history of the OGTT, its reproducibility and the many factors that can impact its results with an emphasis on pregnancy.https://www.mdpi.com/2077-0383/9/11/3451oral glucose tolerance testreproducibilitydiabetesgestational diabetes
collection DOAJ
language English
format Article
sources DOAJ
author Delia Bogdanet
Paula O’Shea
Claire Lyons
Amir Shafat
Fidelma Dunne
spellingShingle Delia Bogdanet
Paula O’Shea
Claire Lyons
Amir Shafat
Fidelma Dunne
The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
Journal of Clinical Medicine
oral glucose tolerance test
reproducibility
diabetes
gestational diabetes
author_facet Delia Bogdanet
Paula O’Shea
Claire Lyons
Amir Shafat
Fidelma Dunne
author_sort Delia Bogdanet
title The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
title_short The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
title_full The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
title_fullStr The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
title_full_unstemmed The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
title_sort oral glucose tolerance test—is it time for a change?—a literature review with an emphasis on pregnancy
publisher MDPI AG
series Journal of Clinical Medicine
issn 2077-0383
publishDate 2020-10-01
description Globally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is linked to the rise in obesity rates among women of reproductive age. GDM poses a major global health problem due to the related micro- and macro-vascular complications of subsequent Type 2 diabetes and the impact on the future health of generations through the long-term impact of GDM on both mothers and their infants. Therefore, correctly identifying subjects as having GDM is of utmost importance. The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing gestational diabetes for decades. However, this test is deeply flawed. In this review, we explore a history of the OGTT, its reproducibility and the many factors that can impact its results with an emphasis on pregnancy.
topic oral glucose tolerance test
reproducibility
diabetes
gestational diabetes
url https://www.mdpi.com/2077-0383/9/11/3451
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