FGF Signaling in Lung Development and Disease: Human Versus Mouse

FGF Signaling in Lung Development and Disease: Human Versus Mouse

Fibroblast growth factor 10 (FGF10) plays an important role in mouse lung development, injury, and repair. It is considered the main morphogen driving lung branching morphogenesis in rodents. While many studies have found FGF10 SNPs associated with COPD and branch variants in COPD smokers, there is...

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Bibliographic Details
Main Authors: Soula Danopoulos, Jessica Shiosaki, Denise Al Alam
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
FGF10
human lung
development
disease
FGF signaling
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00170/full

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