Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature
Waldenstrom macroglobulinemia (WM) is a variant of lymphoplasmacytic lymphoma. In WHO classification of hematolymphoid malignancy 2016, WM has been placed in between lymphoma and plasma cell myeloma under the broad heading “Neoplasms of mature lymphocytes”. This is a rare and slowly progressive diso...
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Wolters Kluwer Medknow Publications
2018-01-01
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doaj-d1fcdaf9bb5646c1b447f861986150eb2021-08-09T09:51:23ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282018-01-0122879010.4103/CDR.CDR_43_17Waldenstrom macroglobulinemia with herpes zoster, a case report and review literatureAmar RanjanRaja PramanikMeenakshi WadhwaniLawanya RanjanRimlee DuttaWaldenstrom macroglobulinemia (WM) is a variant of lymphoplasmacytic lymphoma. In WHO classification of hematolymphoid malignancy 2016, WM has been placed in between lymphoma and plasma cell myeloma under the broad heading “Neoplasms of mature lymphocytes”. This is a rare and slowly progressive disorder, which needs therapy only when symptoms appear. The average age of diagnosis is 60–70 years. WM may progress to lymphoma in 2% cases per year. Here, we are discussing a case of WM having typical findings of this rare disease, who presented with 10%–12% plasma cell in bone marrow aspirate smear, high immunoglobulin M, high beta 2 microglobulin, bilateral axillary lymphadenopathy and gastrointestinal bleeding. At present, the patient is on chlorambucil plus prednisolone therapy and is doing well. Typically, this case presented with lesions of herpes zoster, which makes this case further uncommon.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2018;volume=2;issue=2;spage=87;epage=90;aulast=Ranjanherpes zosterimmunoglobulin m monoclonal gammopathylymphoplasmacytic lymphomawaldenstrom macroglobulinemia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Amar Ranjan Raja Pramanik Meenakshi Wadhwani Lawanya Ranjan Rimlee Dutta |
spellingShingle |
Amar Ranjan Raja Pramanik Meenakshi Wadhwani Lawanya Ranjan Rimlee Dutta Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature Clinical Dermatology Review herpes zoster immunoglobulin m monoclonal gammopathy lymphoplasmacytic lymphoma waldenstrom macroglobulinemia |
author_facet |
Amar Ranjan Raja Pramanik Meenakshi Wadhwani Lawanya Ranjan Rimlee Dutta |
author_sort |
Amar Ranjan |
title |
Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature |
title_short |
Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature |
title_full |
Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature |
title_fullStr |
Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature |
title_full_unstemmed |
Waldenstrom macroglobulinemia with herpes zoster, a case report and review literature |
title_sort |
waldenstrom macroglobulinemia with herpes zoster, a case report and review literature |
publisher |
Wolters Kluwer Medknow Publications |
series |
Clinical Dermatology Review |
issn |
2542-551X 2542-5528 |
publishDate |
2018-01-01 |
description |
Waldenstrom macroglobulinemia (WM) is a variant of lymphoplasmacytic lymphoma. In WHO classification of hematolymphoid malignancy 2016, WM has been placed in between lymphoma and plasma cell myeloma under the broad heading “Neoplasms of mature lymphocytes”. This is a rare and slowly progressive disorder, which needs therapy only when symptoms appear. The average age of diagnosis is 60–70 years. WM may progress to lymphoma in 2% cases per year. Here, we are discussing a case of WM having typical findings of this rare disease, who presented with 10%–12% plasma cell in bone marrow aspirate smear, high immunoglobulin M, high beta 2 microglobulin, bilateral axillary lymphadenopathy and gastrointestinal bleeding. At present, the patient is on chlorambucil plus prednisolone therapy and is doing well. Typically, this case presented with lesions of herpes zoster, which makes this case further uncommon. |
topic |
herpes zoster immunoglobulin m monoclonal gammopathy lymphoplasmacytic lymphoma waldenstrom macroglobulinemia |
url |
http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2018;volume=2;issue=2;spage=87;epage=90;aulast=Ranjan |
work_keys_str_mv |
AT amarranjan waldenstrommacroglobulinemiawithherpeszosteracasereportandreviewliterature AT rajapramanik waldenstrommacroglobulinemiawithherpeszosteracasereportandreviewliterature AT meenakshiwadhwani waldenstrommacroglobulinemiawithherpeszosteracasereportandreviewliterature AT lawanyaranjan waldenstrommacroglobulinemiawithherpeszosteracasereportandreviewliterature AT rimleedutta waldenstrommacroglobulinemiawithherpeszosteracasereportandreviewliterature |
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1721214670024474624 |