A case of acute hemolytic transfusion reaction due to anti-Di antibody -A case report-

• Main Authors: Sung Ha Mun, Seung Hwan Lee, Min Young No
• Format: Article
• Language: English
• Published: Korean Society of Anesthesiologists 2012-10-01
• Series: Korean Journal of Anesthesiology
• Subjects: anti-di antibody; antibody screening test; hemolytic transfusion reaction
• Online Access: http://ekja.org/upload/pdf/kjae-63-353.pdf

Many medical institutions in Korea have recently been performing an antibody screening test as one of the essential elements of a pre-transfusion test. The Dia antigen is well known as one of the antigens with low incidence among Caucasians; however, it has been discovered with a relatively higher incidence among Mongoloid populations. The frequency of the Dia antigen among the Korean population is estimated to be 6.4-14.5%. But in Korea, a screening panel of cells from abroad without Dia positive cells has been commonly used when a patient has an unexpected antibody screening test. Here we report a case of acute hemolytic transfusion reaction due to Anti-Dia antibody. To prevent other transfusion reaction by anti-Dia antibody, addition of Dia positive cells as unexpected antibody screening test is recommended.