Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma.

BACKGROUND: Common variants in DNA may predispose to onset and progression of neuroblastoma (NB). The genotype GG of single nucleotide polymorphism (SNP) rs1800795 (-174 G>C) in interleukin (IL)-6 promoter has been associated with lower survival of high-risk NB. RESULT: To evaluate the impact of...

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Bibliographic Details
Main Authors: Francesca Totaro, Flora Cimmino, Piero Pignataro, Giovanni Acierno, Marilena De Mariano, Luca Longo, Gian Paolo Tonini, Achille Iolascon, Mario Capasso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804531?pdf=render