Prevalence and pathologic effects of colibactin and cytotoxic necrotizing factor-1 (Cnf 1) in Escherichia coli: experimental and bioinformatics analyses

Prevalence and pathologic effects of colibactin and cytotoxic necrotizing factor-1 (Cnf 1) in Escherichia coli: experimental and bioinformatics analyses

Abstract Background The colibactin and cytotoxic necrotizing factor 1 (Cnf 1) are toxins with cell cycle modulating effects that contribute to tumorgenesis and hyperproliferation. This study aimed to investigate the prevalence and pathologic effects of Cnf 1 and colibactin among hemolytic uropathoge...

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Bibliographic Details
Main Authors: Radwa N. Morgan, Sarra E. Saleh, Hala A. Farrag, Mohammad M. Aboulwafa
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Gut Pathogens
Subjects:
Uropathogenic E. coli (UPEC)
Cytotoxic necrotizing factor-1 (Cnf 1)
Colibactin (pks island)
Rat ascending UTI model
Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s13099-019-0304-y

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