The interplay between chondrocyte redifferentiation pellet size and oxygen concentration.
Chondrocytes dedifferentiate during ex vivo expansion on 2-dimensional surfaces. Aggregation of the expanded cells into 3-dimensional pellets, in the presence of induction factors, facilitates their redifferentiation and restoration of the chondrogenic phenotype. Typically 1×10(5)-5×10(5) chondrocyt...
Main Authors: | Betul Kul Babur, Parisa Ghanavi, Peter Levett, William B Lott, Travis Klein, Justin J Cooper-White, Ross Crawford, Michael R Doran |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3598946?pdf=render |
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