Maternal Immune Activation Induces Neuroinflammation and Cortical Synaptic Deficits in the Adolescent Rat Offspring

Maternal Immune Activation Induces Neuroinflammation and Cortical Synaptic Deficits in the Adolescent Rat Offspring

Maternal immune activation (MIA), induced by infection during pregnancy, is an important risk factor for neuro-developmental disorders, such as autism. Abnormal maternal cytokine signaling may affect fetal brain development and contribute to neurobiological and behavioral changes in the offspring. H...

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Bibliographic Details
Main Authors: Magdalena Cieślik, Magdalena Gąssowska-Dobrowolska, Henryk Jęśko, Grzegorz A. Czapski, Anna Wilkaniec, Aleksandra Zawadzka, Agnieszka Dominiak, Rafał Polowy, Robert K. Filipkowski, Paweł M. Boguszewski, Magdalena Gewartowska, Małgorzata Frontczak-Baniewicz, Grace Y. Sun, David Q. Beversdorf, Agata Adamczyk
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
maternal immune activation
lipopolysaccharide
synaptic proteins
autism
Online Access:https://www.mdpi.com/1422-0067/21/11/4097

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https://www.mdpi.com/1422-0067/21/11/4097

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