Partial reduction of microglia does not affect tau pathology in aged mice
Abstract Background Activation of inflammation pathways in the brain occurs in Alzheimer’s disease and may contribute to the accumulation and spread of pathological proteins including tau. The goal of this study was to identify how changes in microglia, a key inflammatory cell type, may contribute t...
Main Authors: | Rachel E. Bennett, Annie Bryant, Miwei Hu, Ashley B. Robbins, Sarah C. Hopp, Bradley T. Hyman |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1348-5 |
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